The IONA® Screening Test - £400

The IONA® Screening Test £400

The IONA® test is a safe non-invasive and accurate screening test for Downs Syndrome, Edwards’ Syndrome and Patau’s Syndrome.  We can offer this test at home to anyone who has had a scan to date the pregnancy.  The ideal time is around 10 weeks.  The test is more accurate than the standard combined test offered by the NHS as it uses DNA from the baby found in the mother’s blood to assess risk which the combined test does not.


According to the  International Society for Prenatal Diagnosis (ISPD) and American College of Medical Genetics and Genomics (ACMG) support offering NIPT as a first-line screen., non-invasive prenatal testing (like ) is appropriate as a Primary Screening Test for pregnant women of all ages. Down Syndrome and certain other chromosomal conditions occur more frequently in babies born to mothers over 35 years old. Other conditions for which NIPT  screens – such as microdeletion syndromes – occur with the same frequency in babies, regardless of the mother’s age.

To Contact us for more information to know about these blood test call  📞 01138301371  to speak with the Healthcare Professional

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Are NIPT Tests available on the NHS Treatment?

NHS will only provide a Combined test or Quadruple blood screening test the blood test to indicate the likelihood that your baby has Down’s Syndrome only if there is a risk considered HIGH, only then the patients will then be offered an invasive test called an Amniocentesis or chorionic villus sampling (CVS). Both these test procedures carry a  High risk of miscarriage, that's is why most parents are going for the NIPT test. NIPT screening test carries no risk to Mum or Baby infant with the results arriving in 7 working days.

The NHS is currently unable to provide this test due to the costs involved, although most private healthcare professionals recommend it for the Peace of mind 


Traditional screening offered during pregnancy is currently called the combined test. This is an ultrasound scan to measure the nuchal translucency (NT) and a blood test. This is much less accurate than NIPT and it only detects around 85% of babies with Down’s syndrome.

The IONA® test has a higher detection rate than the current combined test offered to pregnant women. This means that fewer pregnant women will undergo unnecessary invasive follow-up procedures such as amniocentesis or CVSChorionic villus sampling )  which are stressful, painful and can carry a small risk of miscarriage.

Can I have the IONA® test if I have twins?

The IONA® test is suitable for twin pregnancies. However, in dichorionic twins, the test sensitivity is reduced from >99% to about 95%. Dichorionic means there are two placentas, such as non-identical twins and some identical twins.

Is the IONA® test 100% conclusive?

It is not 100% conclusive due to naturally occurring biological instances where the fetal DNA differs from the placental DNA.


Why to Choose IONA Screening test

  • Safe: non-invasive with no risk of miscarriage
  • Fast: results available in 3-5 working days
  • Accurate: greater than 99% at detecting trisomy conditions (trisomy 21, 18 and 13) and greater than 97% at detecting fetal sex (optional)
  • Local: the IONA® test is performed in a laboratory local to you, not shipped to US or China
  • Quality: the IONA® test is a regulated screening test which is CE marked  ,Its From 10 weeks gestation a small blood sample is taken from the mother’s arm and sent to a local laboratory for analysis with the IONA® test. The DNA from the mother’s blood is extracted and the test is performed on the small amount of DNA.  During pregnancy, the placenta leaks fetal cell-free DNA which circulates in the maternal bloodstream. As a result, a maternal plasma sample contains a mixture of fetal and maternal circulating DNA.  The IONA® test directly measures the amount of cell-free DNA and can detect small changes in the DNA ratio between the maternal and cell-free DNA when a fetal trisomy 21, 18 or 13 is present.

How are the IONA® results reported?

  • The IONA® Software for analysis calculates the relative amount of chromosomes 21, 18 and 13 to calculate a likelihood ratio to predict the presence of a trisomy. This figure is then combined with the mother’s age to calculate the probability of the foetus being affected.

What is the false positive rate?

Less than 1% of pregnant women may receive a high-risk result from the IONA® test and then go onto to have a follow-up invasive test which confirms that the fetus is not affected with trisomy 21, 18 or 13.

For further information, please visit the test provider's website using the links referenced below:

How the test works

  • Low Risk: means that it is very unlikely your pregnancy is affected by trisomy 21, 18 or 13.
  • High risk: means that your pregnancy is at increased risk for trisomy 21, 18 or 13 and the result should be confirmed by a follow up invasive such as amniocentesis.
  • No result: Very occasionally there is insufficient placental DNA in the sample to obtain a result. Women may be asked back by your healthcare provider for a further blood sample.

Gender Confirmation

The very earliest you can have a scan to test for a Baby’s Gender  Reveal is around 16 weeks and the NHS don’t tend to provide gender confirmation until 20 weeks. A NIPT test can be performed from as early as 10 weeks, with the results arriving in 7 working days.

What do about my Regular NHS 12 weeks scan and NT measurements scans?

If you are having NIPT Test or you have got negative or Low-risk result on the Non-Invasive Prenatal  Test you should still attend and not miss your regular 12 week NHS  scan and the NT measurements.

What if the sample fails?

Statistically there is a 3 to 4% failure rate that there is not enough cell free DNA in the blood sample to analyse. In this event a new sample will need to be taken again at no extra cost.

What if I have a high BMI?

The relative proportion of cell-free fetal DNA is reduced in women with a high BMI as they have more of their own cell-free DNA circulating in their blood. This may increase the chance of getting an inconclusive result.


Please note

  • We will require details of your GP / Health Care Professional, which may be requested prior to or at the time of the scan.
  • This scan requires access to the area of interest, therefore it is recommended to wear loose clothing to facilitate this process.
  • Blood results require interpretation and All results should be shared with your regular healthcare professional / GP / Fertility specialist.
  • All of our first line ultrasound scans & health Blood tests are optional. You must be at least 16 years old and you should have no existing medical condition or treatment pending that relates to the scan/blood test  you are booking. If you are in any doubt about having any type of test, you should consult your GP.
  • Genetic counselling is not provided as part of this Blood test Services. Customers regular Healthcare professional / GP / Fertility specialist is responsible for ensuring appropriate counselling provided to the patient.

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