PrenatalSAFE® 3

PrenatalSAFE® NIPT £300

Non-invasive prenatal tests (NIPT) like PrenatalSafe have been shown to perform better than traditional prenatal screening methods, and they avoid the risk of miscarriage associated with invasive diagnostic procedures such as amniocentesis and chorionic villus sampling (CVS).

According to the  International Society for Prenatal Diagnosis (ISPD) and American College of Medical Genetics and Genomics (ACMG) support offering NIPT as a first-line screen., non-invasive prenatal testing  is appropriate as a Primary Screening Test for pregnant women of all ages. Down Syndrome and certain other chromosomal conditions occur more frequently in babies born to mothers over 35 years old. Other conditions for which NIPT  screens – such as microdeletion syndromes – occur with the same frequency in babies, regardless of the mother’s age.

The PrenatalSAFE  non-invasive prenatal test screens for aneuploidies 

PrenatalSAFE is a test indicated for patients with:

• Maternal age-related risks (≥35 years)
• Ultrasound finding(s) suggestive of an aneuploidy
• Personal or family history of chromosomal aneuploidy
• One of the partners with a balanced chromosome 13 or 21 Robertson translocation
• Low-risk pregnancies

PrenatalSAFE 3 without Scan - £ 300

PrenatalSAFE 3  with Scan  -  £ 350

Is done for the screening of aneuploidies such as Downs syndrome, Edwards syndrome, Patau syndrome with a  Dating Scan Included 

  • 15 -minute Appointment with a Qualified Health Professional
  • 1 sample of blood will be taken from the arm of the mother
  • 10-week prenatal genetic test (singleton pregnancy only)
  • If Fetal DNA sex Aneuploidies of Baby needed please  upgrade to Prenatal safe 5
  • Results of test  will be emailed to the client

For further information, please see the test provider’s Technical Analysis Report by clicking here.

To Book this NIPT Test, please Click   BOOK NOW

 

PrenatalSAFE 5 without Scan - £ 350

PrenatalSAFE 5  with Scan  -  £ 400

Screens for aneuploidies such as Downs syndrome, Edwards syndrome, Patau syndrome and also the screening of aneuploidies such as Turner Syndrome, Jacobs syndrome and Klinefelter Syndromes, plus Trisomy X with a  Dating scan

  • 15 -minute Appointment with a Qualified Health Professional
  • 1 sample of blood will be taken from the arm of the mother
  • with this package is Included DNA sexing of Baby (singleton pregnancy only)
  • Results of test will be emailed to the client
  • This test includes the determination of fetal sex.
  • a prenatal genetic test (singleton pregnancy only)
  • For further information,Click HERE or the image to download a copy of the brochure.

For further information, please see the test provider’s Technical Analysis Report by clicking here.

To Book this NIPT Test, please Click   BOOK NOW

 

PrenatalSAFE 5 plus without Scan - £ 450

PrenatalSAFE 5 plus   with Scan  -  £ 500

Screens for aneuploidies such as Downs syndrome, Edwards syndrome, Patau syndrome and also the screening of aneuploidies such as Turner Syndrome, Jacobs syndrome and Klinefelter Syndromes, plus Trisomy X , Panel of 6 microdeletions (+Trisomies 9 and 16 ) with a option of  Dating scan

  • 15 -minute Appointment with a Qualified Health Professional
  • 1 sample of blood will be taken from the arm of the mother
  • with this package is Included DNA sexing of Baby (singleton pregnancy only)
  • 6-panel microdeletions
    - DiGeorge syndrome, 
    - 1p36 deletion syndrome,
    - Angelman Syndrome,
    - Prader-Willi syndrome,
    - Cri du Chat syndrome
    - Wolf-Hirschhorn Syndrome.
  • Results of test emailed to the client
  • This test includes the determination of fetal sex.
  • a prenatal genetic test (singleton pregnancy only)
  • For further information,Click HERE or the image to download a copy of the brochure.

For further information, please see the test provider’s Technical Analysis Report by clicking here.

To Book this NIPT Test, please Click   BOOK NOW

  

PrenatalSAFE Karyo without ultrasound  - £550 

PrenatalSAFE Karyo with Ultrasound - £550 

Genome-wide NIPT that provides karyotype-level insight and screens all the conditions included in PrenatalSafe 5, plus less frequent chromosomal aneuploidies such as Trisomy’s 1 to 22. plus less frequent chromosomal aneuploidies such as Trisomy’s 1 to 22 with a  Dating scan

  • Maternal age-related risks (≥35 years)
  • Ultrasound finding(s) suggestive of an aneuploidy
  • Personal or family history of chromosomal aneuploidy
  • One of the partners with a balanced chromosome 13 or 21 Robertson translocation
  • Low-risk pregnancies
  • For further information, click HERE or the image to download a copy of the brochure.

For further information, please see the test provider’s Technical Analysis Report by clicking here.

To Book this NIPT Test, please Click   BOOK NOW

 

PrenatalSAFE KARYO PLUS with Ultrasound   - £600

PrenatalSAFE Karyo with Ultrasound - £650 

Karyo Plus Genome-wide NIPT that provides karyotype-level insight + panel 9 Microdeletions**Test Analyses every chromosome in the genome as well as 9 clinically significant microdeletion syndromes DiGeorge, Cri-du-chat, Prader-Willi, Angel man, 1p36 deletion, Wolf-Hirschhom, Jacobsen, Langer-Giedion, Smith-Magenis Syndromes with a Dating scan

  • 9-panel microdeletions:

    - DiGeorge syndrome,
    - 1p36 deletion syndrome,
    - Angelman Syndrome,
    - Prader-Willi syndrome,
    - Cri du Chat syndrome
    - Wolf-Hirschhorn Syndrome.
    - Langer-Gleidon syndrome,
    - Jacobsen syndrome and
    - Smith-Magenis syndrome
  • Personal or family history of chromosomal aneuploidy
  • One of the partners with a balanced chromosome 13 or 21 Robertson translocation
  • Low-risk pregnancies
  • For further information, Click HERE or the image to download a copy of the brochure.

For further information, please see the test provider’s Technical Analysis Report by clicking here.

To Book this NIPT Test, please Click   BOOK NOW

 

PrenatalSAFE® COMPLETE  – £ 900

PrenatalSAFE® Karyo + GeneSAFE™ Complete

  • This test screens for 5 common inherited recessive genetic disorders, such as Cystic Fibrosis, Beta-Thalassemia, Sickle cell anaemia, Deafness autosomal recessive type 1a and 1b.
  • Allows detection of common inherited disorders within the foetus.
  • Genes screened: CFTR, CX26 (GJB2), CX30 (GJB6), HBB .
  • For further information, Click HERE or the image to download a copy of the brochure.

For further information, please see the test provider’s Technical Analysis Report by  clicking here

To Book this NIPT Test, please Click   BOOK NOW

 

PrenatalSAFE® COMPLETE Plus – £ 1000

( PrenatalSAFE® Karyo Plus + GeneSAFE™ Complete )

This test screens for 44 severe genetic disorders due to de novo mutations (a gene mutation that is not inherited) in 25 genes. 

  • Many disorders screened with GeneSafe De Novo are not typically associated with abnormal prenatal ultrasound findings (especially in the first trimester), or may not be evident until the late second/third trimester when confirmatory invasive testing can pose a risk of pre-term birth, or baby’s health after delivery.
  • Genes screened: ASXL1, BRAF, CBL, CHD7, COL1A1, COL1A2 , COL2A1, FGFR2, FGFR3, HDAC8, JAG1, KRAS, MAP2K1, MAP2K2, MECP2, NIPBL, NRAS, NSD1, PTPN11, RAF1, RIT1, SETBP1, SHOC2, SIX3, SOS1
  • For further information,Click HERE or the image to download a copy of the brochure.

For further information, please see the test provider’s Technical Analysis Report by  clicking here

To Book this NIPT Test, please. Click   BOOK NOW

 

PrenatalSafe Facilitates Early Diagnosis Of Single-Gene Disorders. The First Non-Invasive Prenatal Test that Screens Multiple Genes For Mutations Causing Severe Genetic Disorders In The Foetus.

Prenatalsafe works as a complementary screen to traditional and genome-wide NIPT PrenatalSafe KARYO. GeneSafe screens for several life-altering genetic disorders that are not screened with current NIPT technology, allowing for a more complete picture of the risk of a pregnancy being affected by a genetic disorder.

Clinical Performance Report for PrenatalSAFE®  NIPT

To Contact us for more information to know about these blood tests call  📞 01138301371  to speak with the Healthcare Professional. 

What is diagnosed?

PrenatalSAFEis a Non-Invasive Prenatal test that detects common chromosomal aneuploidies on chromosome 21 (Down Syndrome), chromosome 18 (Edwards Syndrome) and chromosome 13 (Patau Syndrome) and those of the X and Y sexual chromosomes such as Turner Syndrome, Klinefelter Syndrome and Jacobs Syndrome, by analyzing fetal DNA in circulation.

PrenatalSAFE offers a further second level of testing that diagnoses structural chromosomal alterations, among which a few common microdeletion syndromes (DiGeorge Syndrome, Cri-du-chat Syndrome, Prader-Willi Syndrome, Angelman Syndrome, 1p36 deletion Syndrome, WolfHirschorn Syndrome), and Trisomy 9 and 16.

PrenatalSAFE can find chromosomal aneuploidies even on low quantities of fetal DNA (2%), in comparison to other tests that require >4% of fetal DNA.

To Book this NIPT Test, please Click   BOOK NOW

 

 What do about my Regular NHS 12 weeks scan and NT measurements scans?

If you are having NIPT Test or you have got negative or Low-risk results on the Non-Invasive Prenatal  Test you should still attend and not miss your regular 12-week NHS  scan and the NT measurements.

For further information, please see the test provider’s Technical Analysis Report by clicking here.

Genetic counselling is available to all PrenatalSAFE clients. Contact us about this service and we will put you in touch with someone who is trained to talk you through your result when there is a Positive Outcomes. 

What do about my Regular NHS 12 weeks scan and NT measurements scans?

If you are having NIPT Test or you have got negative or Low-risk results on the Non-Invasive Prenatal  Test you should still attend and not miss your regular 12-week NHS  scan and the NT measurements. 

What if the sample fails?

Statistically, there is a 3 to 4% failure rate because there is not enough cell-free DNA in the blood sample to analyse. In this event, a new sample will need to be taken again at no extra cost.

What if I have a high BMI?

The relative proportion of cell-free fetal DNA is reduced in women with a high BMI as they have more of their own cell-free DNA circulating in their blood. This may increase the chance of getting an inconclusive result.

 

Please note

  • We will require details of your GP / Health Care Professional, which may be requested prior to or at the time of the scan.
  • This scan requires access to the area of interest, therefore it is recommended to wear loose clothing to facilitate this process.
  • Blood results require interpretation and All results should be shared with your regular healthcare professional / GP / Fertility specialist.
  • All of our first-line ultrasound scans & health Blood tests are optional. You must be at least 16 years old and you should have no existing medical condition or treatment pending that relates to the scan/blood test you are booking. If you are in any doubt about having any type of test, you should consult your GP.
  • The Geneticist, in the context of Genetic Counselling, will explain in detail the test result and advise to confirm the result by invasive prenatal diagnosis. is provided as part of this Blood test Service. The customer's regular Healthcare professional / GP / Fertility specialist is responsible for ensuring appropriate counselling is provided to the patient.
  • Please note: £50 non-refundable deposit is payable upon booking. Should you wish to alter your appointment time; please give the boutique a minimum of 48 hours' notice. Please refer to the individual boutiques’ opening times. 

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